DNA Narcolepsy Test
$195
Do you struggle with excessive daytime sleepiness?
Narcolepsy is a neurological disorder characterized by extreme daytime sleepiness and uncontrollable episodes of falling asleep. This excessive daytime sleepiness should not be mistaken for the afternoon slump, since neurological defects are responsible for narcolepsy, rather than just sleep deprivation or lack of caffeine!
- Explore the Genetics of Sleep: Learn if you carry the HLA-DQB1*06:02 variant strongly linked to narcolepsy.
- Understand Your Symptoms: Genetic insights for persistent sleepiness, cataplexy, and sleep paralysis.
- Family Planning: Find out the risk of passing on narcolepsy-linked genes.
How it Works
Order your DNA Kit
Place your order online, and we’ll send you a DNA test kit with everything you need to collect your samples.
Collect DNA Samples
Follow the detailed, step-by-step instructions to collect DNA samples using the provided mouth swabs.
Lab Analysis
Use the provided return envelope to mail your DNA samples to our laboratory for analysis.
Receive Results
Download your results from your secure online account as soon as they’re ready.
What is Narcolepsy?
Family members of an affected individual have a 20X – 40X increased risk of developing narcolepsy, indicating a strong genetic basis for the disorder.
Genetics of narcolepsy
The genetic variant most closely associated with narcolepsy is HLA-DQB1*06:02. Individuals with this variant are at 7X to 25X increased risk, although one recent European study indicates a much higher odds ratio of approximately 250-fold.
Understanding Your Results
There are no painful needles or doctor’s appointments required. We provide simple mouth (buccal) swabs to painlessly collect a few cheek cells. Your DNA is inside every one of these cells, and that is all that is required for the analysis.
Frequently Asked Questions
What is the DNA Narcolepsy Test?
The DNA Narcolepsy Test is designed to determine if you carry a specific genetic variant associated with an increased risk of narcolepsy. Narcolepsy is a neurological condition characterized by extreme daytime sleepiness, and this test can help identify a key biological marker for the disorder.
Who should consider taking this test?
This test is for individuals who experience symptoms like excessive daytime sleepiness, sudden muscle weakness (cataplexy), or vivid dreams and want to explore a potential genetic link. It can be a valuable first step in discussing your symptoms with a sleep specialist.
How do I provide a DNA sample for the test?
Providing a sample is quick, easy, and painless. The kit we send you includes a simple mouth swab that you use to collect cells from the inside of your cheek. You can do it yourself in just a few minutes at home.
If I have the genetic variant, does that mean I have narcolepsy?
No, not necessarily. While the vast majority of people with narcolepsy have this gene variant, many people in the general population also carry it without ever developing the disorder. A positive result indicates a significantly increased risk and is a strong piece of evidence, but it is not a diagnosis on its own. The results should always be discussed with a healthcare professional in the context of your symptoms.
How can I use the information from this test?
A positive result, meaning you carry the HLA-DQB106:02* variant, can be a significant finding in the diagnostic process for narcolepsy. It can help explain your symptoms and guide your doctor toward appropriate follow-up testing, such as a sleep study, to confirm a diagnosis and begin an effective treatment plan.
What specific gene does the narcolepsy test analyze?
This test specifically analyzes the Human Leukocyte Antigen (HLA) system, looking for the HLA-DQB1*06:02 variant. This variant is part of the immune system, and its presence is the most significant known genetic risk factor for narcolepsy with cataplexy.
Is your testing facility reputable and accredited?
How will I receive my results?
How long does it take to get results?
Once your sample is received by our laboratory, processing usually takes 6-8 weeks. You will receive an email notification when your results are ready, and you can access your detailed report through a secure online portal.
Is the testing process confidential?
Yes, your confidentiality is guaranteed. From the discreet packaging of the test kit to the secure delivery of your results, we ensure your privacy is protected every step of the way.
Why DNA Tests Direct?
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