DNA Hemochromatosis Test
$195
Are you at risk of excess iron levels?
Discover your risk of hereditary hemochromatosis with our simple and painless home DNA test kit
- Understand Iron Overload: Find out if you are genetically at risk for hereditary hemochromatosis, a condition where your body absorbs too much iron.
- Detects 3 Mutations: Detects three mutations in the HFE gene (C282Y, H63D, and S65C) that are linked to hereditary hemochromatosis.
- Know Early, Act Early: Early detection helps prevent complications like fatigue, memory problems, and heart issues.
How it Works
Order your DNA Kit
Place your order online, and we’ll send you a DNA test kit with everything you need to collect your samples.
Collect DNA Samples
Follow the detailed, step-by-step instructions to collect DNA samples using the provided mouth swabs.
Lab Analysis
Use the provided return envelope to mail your DNA samples to our laboratory for analysis.
Receive Results
Download your results from your secure online account as soon as they’re ready.
What is Hemochromatosis?
Hereditary hemochromatosis is a genetic disorder affecting iron metabolism, causing the body to absorb excessive iron from food. If left untreated, it can lead to serious health problems, including liver disease, heart issues, and diabetes. Early detection and treatment can help prevent these complications.
Hemochromatosis is difficult to diagnose, because it involves symptoms that are also seen in many other health conditions. Early symptoms include fatigue and weakness, depression and memory problems. In severe cases, it can cause heart problems, diabetes, and liver cancer. The disorder is common, affecting approximately 1 in 200 people of Northern European descent.
The HFE Gene & Hemochromatosis
The HFE gene provides instructions for making a protein called HFE, which plays an important role in regulating iron absorption in the body.
Mutations in the HFE gene lead to an overload of iron, causing hereditary hemochromatosis. The most common mutations are C282Y, H63D, and S65C, accounting for approximately 85% of cases.
- C282Y: The most common mutation associated with hereditary hemochromatosis, found in approximately 80-90% of affected individuals.
- H63D: A less common mutation that can also increase iron absorption and lead to hereditary hemochromatosis.
- S65C: A rare mutation that can increase iron absorption and lead to hereditary hemochromatosis, more commonly found in individuals of African or Asian descent.
Understanding Your Results
The test is designed to detect the presence of the C282Y, H63D, and S65C mutations in theHFEgene to identify if you are at risk of developing hereditary hemochromatosis. Your test results will indicate one of the following:
- Normal: You have tested negative for all three mutations and are not at increased risk of developing hereditary hemochromatosis.
- Carrier: You have inherited one defectiveHFEgene and are at risk of passing it to your children. You may also have higher than average iron absorption.
- Affected: You have inherited two defectiveHFEgenes and are at increased risk of developing hereditary hemochromatosis.
Frequently Asked Questions
What will the DNA Hemochromatosis Test tell me?
This at-home DNA test will help you discover if you are at an increased risk of developing hereditary hemochromatosis, a condition that causes your body to absorb too much iron. The test detects three specific mutations in the HFE gene that are responsible for the majority of cases.
Who should consider testing for hereditary hemochromatosis?
This test is recommended for individuals who have a family history of hemochromatosis or those who are experiencing symptoms such as chronic fatigue, joint pain, or abdominal pain that could be related to iron overload. Early detection can lead to better management of the condition.
How is the sample collected for testing?
Collecting a sample is simple and non-invasive. Your kit includes mouth swabs that you will use to painlessly collect a sample of your cheek cells from inside your mouth. This can be done easily at home.
Is this a diagnostic test for hemochromatosis?
While this test identifies the key genetic mutations associated with hereditary hemochromatosis, it is not a diagnostic test on its own. A positive result indicates a high genetic risk, and you should share your results with a healthcare professional who can order further tests to make a formal diagnosis.
How will understanding my genetic risk help me?
Knowing you have a genetic risk for hemochromatosis allows you to take proactive steps to protect your health. You can work with your doctor on monitoring your iron levels and making lifestyle changes to prevent the complications associated with iron overload.
What specific gene mutations does the DNA Hemochromatosis Test identify?
This test detects the three most common mutations in the HFE gene that are linked to hereditary hemochromatosis. These variants are C282Y, H63D, and S65C, which together account for about 85% of cases.
Is your testing facility reputable and accredited?
How will I receive my results?
How long does it take to get results?
Once your sample is received by our laboratory, processing usually takes 6-8 weeks. You will receive an email notification when your results are ready, and you can access your detailed report through a secure online portal.
Is the testing process confidential?
Yes, your confidentiality is guaranteed. From the discreet packaging of the test kit to the secure delivery of your results, we ensure your privacy is protected every step of the way.
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