DNA Anxiety & Depression Test
$149
Discover If You Have the "Grouchy Gene"
Are you struggling with anxiety and depression? Do you feel like you can’t shake off feelings of sadness and irritability? The Anxiety & Depression DNA Test identifies whether you carry the “grouchy” gene linked to an increased risk of anxiety and depression.
- Understand Your Mood: Discover if you have the "grouchy gene," a variant of the SLC6A4 gene linked to serotonin levels and your predisposition for anxiety and depression.
- Personalized Mental Wellness: Understand how your genetics might impact mood and response to antidepressants for informed care.
- Easy At-Home Testing: Collect your DNA with a simple, painless mouth swab and receive confidential results online.
How it Works

Order your DNA Kit
Place your order online, and we’ll send you a DNA test kit with everything you need to collect your samples.

Collect DNA Samples
Follow the detailed, step-by-step instructions to collect DNA samples using the provided mouth swabs.

Lab Analysis
Use the provided return envelope to mail your DNA samples to our laboratory for analysis.

Receive Results
Download your results from your secure online account as soon as they’re ready.
Serotonin and the serotonin receptor
Serotonin is a chemical messenger in the brain that influences your mood, sense of well-being, and happiness. When your body’s serotonin levels are balanced, you’re more likely to feel positive and content.
The SLC6A4 gene provides instructions for making the serotonin transporter, a protein that helps transport serotonin from one brain cell to another. When this gene is working properly, our serotonin levels are balanced, and we feel happy, relaxed, and content.
The “grouchy” gene, also known as the S-allele, is a variation of the SLC6A4 gene that affects how the brain processes serotonin. People with the “grouchy” gene may be more prone to feelings of sadness and anxiety. They may also have a harder time responding to antidepressant medications.

The SLC6A4 Gene and Serotonin Regulation
The “grouchy” gene is a variation of the SLC6A4 gene that affects your brain’s ability to regulate serotonin levels. If you carry this gene, you may be more prone to feelings of anxiety, depression, and irritability
Understanding Your Results
The SLC6A4 gene is found on chromosome 17. Since we inherit chromosomes in pairs – one from each parent – every individual carries two copies of theSLC6A4gene. This test examines the 5-HTTLPR region of theSLC6A4gene to identify if you have the “grouchy” gene variant. Your results will indicate whether you have:
- Two copies of the “grouchy” gene: This may increase your risk of anxiety and depression, as you may have lower levels of serotonin in your brain.
- One copy of the S-allele and one copy of the L-allele (SL): This may also increase your risk, although to a lesser extent, as you may have slightly higher levels of serotonin compared to those with the SS variant.
- Two copies of the L-allele (LL):This may indicate a lower risk of anxiety and depression, as you may have normal or higher levels of serotonin in your brain.
If you have the “grouchy” gene variant, you may be more likely to experience anxiety and depression. However, having this variant doesn’t mean you’ll definitely develop these conditions, and many people with the variant lead happy and healthy lives.
Frequently Asked Questions
What does the DNA Anxiety & Depression Test analyze?
This test examines the SLC6A4 gene to reveal how your DNA might affect your mood and emotional responses. It specifically looks for a common variation, sometimes nicknamed the “grouchy gene,” that can influence how you handle stress and your predisposition to feelings of anxiety and depression.
Who should consider taking this test?
This test is for anyone curious about the connection between their genes and their emotional landscape. If you’ve ever wondered why you react to stress differently than others, or if you feel you might have a natural tendency toward moodiness or anxiety, this test can provide valuable genetic insights.
What specific gene is tested?
This test focuses on the SLC6A4 gene, which is involved in transporting serotonin, a chemical in the brain that plays a significant role in mood regulation. Variants in this gene have been linked to differences in how individuals handle stress and their overall emotional disposition.
Is this a diagnostic test for anxiety or depression?
It is important to understand that this is not a diagnostic tool. The test reveals your genetic predisposition, not a definitive health condition. For any mental health concerns, you should always consult with a qualified healthcare professional.
How can I use the results of this test?
The results can be a starting point for self-discovery and understanding. They can empower you to explore your emotional responses in a new light and can be a useful tool for discussions with health and wellness professionals to support your overall well-being.
Does having the "grouchy gene" mean I'm destined to be unhappy?
Not at all. Your genes are not your destiny. This test simply reveals a predisposition, not a predetermined outcome. Many people with the “short” allele lead happy, fulfilling lives. This information is a tool for self-awareness, empowering you to better understand your emotional tendencies and build resilience.
Is your testing facility reputable and accredited?
How will I receive my results?
How long does it take to get results?
Once your sample is received by our laboratory, processing usually takes 6-8 weeks. You will receive an email notification when your results are ready, and you can access your detailed report through a secure online portal.
Is the testing process confidential?
Yes, your confidentiality is guaranteed. From the discreet packaging of the test kit to the secure delivery of your results, we ensure your privacy is protected every step of the way.











