DNA Celiac Disease Test$249
DNA Celiac Disease Test
$249
Discover your genetic risk for Celiac Disease. This simple DNA test provides insights into your gluten sensitivity from the comfort of your home.
Discover Your Celiac Disease Risk
Are you experiencing digestive discomfort, fatigue, or other unexplained symptoms? This at-home DNA test identifies key genetic markers associated with celiac disease to determine your risk of developing this condition.
- Genetic Insights: Identifies three high-risk variants of the HLA-DQA1 and HLA-DQB1 genes.
- Gluten-Free Friendly: No need to consume gluten, making it ideal for those already on a gluten-free diet.
- Painless Sampling: Collect your DNA samples with easy-to-use mouth swabs – no blood or needles required.
How it works
Collect DNA Samples
Your DNA kit includes everything you need to collect easy mouth swabs in the privacy of your home.
Mail samples to the lab
When you're finished collecting your DNA samples, simply mail them to the lab for analysis.
Receive your results
Receive confidential results in your secure online portal within 6-8 weeks after testing begins.
What is Celiac Disease?
Celiac disease is an autoimmune disorder affecting the body’s response to gluten – a protein found in wheat, rye, barley, and often food additives. This condition impacts approximately 1 in 100 people worldwide, but surprisingly, only about 30% are properly diagnosed.
When someone with celiac disease consumes gluten, their immune system launches an attack on the small intestine. This attack leads to inflammation and damage to the villi, the tiny, finger-like projections that line the intestine and are responsible for absorbing essential nutrients. Over time, this damage can prevent the body from getting the nutrients it needs, putting you at risk of:
- Vitamin & mineral deficiencies (like iron and calcium)
- Digestive problems (diarrhea, constipation, gas, bloating)
- Weight loss or gain
- Fatigue
- Anemia
- Osteoporosis (bone loss)
- Increased risk of other autoimmune diseases
Celiac disease affects people of all ages, and symptoms can vary widely. Some people may have no noticeable symptoms at all. If left untreated, celiac disease increases the risk of other serious health conditions such as osteoporosis, infertility, neurological diseases, and increased risk of intestinal cancers.
The Genetics of Celiac Disease
Celiac disease tends to run in families, which means if someone in your family has it, you’re more likely to have it too. This increased risk is tied to specific genes that influence how your immune system interacts with gluten.
The genes involved, HLA-DQA1 and HLA-DQB1, are critical for immune function, helping your body distinguish its own cells from potentially harmful invaders. In people with celiac disease, these proteins can mistakenly identify gluten as a threat, triggering an immune response that attacks the small intestine,
Our DNA test analyzes three high-risk variants within the HLA-DQA1 and HLA-DQB1 genes linked to celiac disease:
- HLA-DQA1*05
- HLA-DQB1*02
- HLA-DQB1*0302
Carrying one or more of these genetic variants increases your risk of developing celiac disease. However, it’s important to note that genetics alone doesn’t determine whether you’ll develop the condition. While these genetic markers increase susceptibility, not everyone with these variants will develop celiac disease.
Decoding Your Celiac Risk Test Results
Your results report will explain the specific gene variants detected and provide clear details on your risk level for celiac disease.
| Gene | Variants | Description |
|---|---|---|
| HLA-DQA1 | HLA-DQA1*05 | This variant is a common indicator of celiac disease, found in approximately 90% of diagnosed individuals. |
| HLA-DQB1 | HLA-DQB1*02, HLA-DQB1*0302 | These variants are associated with an increased likelihood of developing celiac disease, particularly HLA-DQB1*02 in individuals of Northern European descent. |
Frequently Asked Questions
How long does it take to get results?
Once your sample is received by our laboratory, processing usually takes 6-8 weeks. You will receive an email notification when your results are ready, and you can access your detailed report through a secure online portal.
Is my genetic information kept private?
We take data privacy seriously. Your results are confidential and only shared with you. We do not share your results with insurance companies, employers, or any other third parties.
Why DNA Tests Direct?
Accredited Excellence
Our laboratory holds globally recognized accreditations including AABB, CAP, CLIA, SCC, and ISO17025, ensuring accurate results for every test.
Your Privacy, Protected
Your privacy is our top priority. Our secure, accredited laboratory and password-protected online portal guarantee that your results are shared only with you.
Expert Support
Our dedicated customer care team is here to support you through the process, answer your questions, and provide any assistance you need.