DNA Alzheimer’s Disease Test$195
DNA Alzheimer’s Disease Test
$195
Discover if you are genetically predisposed to late-onset Alzheimer’s with this simple, at-home DNA test. This test detects whether you carry the APOE4 variant, a key genetic risk factor linked to an increased risk of Alzheimer’s disease.
Discover Your Alzheimer's Risk
The DNA Alzheimer’s Disease Test is a simple, at-home DNA test that helps you understand your genetic risk of developing late-onset Alzheimer’s disease.
- Identifies the APOE4 Variant: Detects whether you carry APOE e4, a strong risk factor for late-onset Alzheimer's disease.
- Simple and Private: Collect your samples from the comfort of your home, no blood or needles required.
- Online Results: Receive confidential results through a secure online portal, ensuring your privacy and peace of mind at every step.
- Painless Sampling: Collect your DNA samples with easy-to-use mouth swabs – no blood or needles required.
How it works
Collect DNA Samples
Your DNA kit includes everything you need to collect easy mouth swabs in the privacy of your home.
Mail samples to the lab
When you're finished collecting your DNA samples, simply mail them to the lab for analysis.
Receive your results
Receive confidential results in your secure online portal within 6-8 weeks after testing begins.
What is Alzheimer's Disease?
Alzheimer’s disease is a progressive brain disorder that gradually destroys memory and other important mental functions. As the most common form of dementia, Alzheimer’s disease accounted for 60–70% of approximately 55 million dementia cases. In most cases, symptoms appear after age 65, a condition known as late-onset Alzheimer’s disease.
The Role of APOE in Alzheimer’s Disease
The APOE gene has an important role in transporting cholesterol and fats in your body and greatly influences your Alzheimer’s disease risk. There are three types of APOE alleles (gene variants) you can inherit from your parents: e2, e3, and e4. Each of these alleles affects your Alzheimer’s disease risk differently:
- APOE e2: This variant is relatively rare and is associated with a decreased risk of Alzheimer’s. It may even delay the onset of symptoms, offering some protective benefits against the disease.
- APOE e3: This is the most commonly found allele and is generally believed to have a neutral impact on the risk of developing Alzheimer’s disease.
- APOE e4: This allele significantly increases the risk of Alzheimer’s. People with one copy of APOE e4 may see their risk double or triple, while those with two copies (inherited from both parents) face a risk increase of 10–15 times compared to those without this allele.
Understanding Your Results
Your DNA test results will indicate which APOE alleles you carry. Everyone inherits two APOE variants, one from each parent. Here’s what your results mean:
| Genes | Variants | Description |
|---|---|---|
| APOE | e4/e4 | You have two copies of the APOE e4 allele, which significantly increases your risk of developing Alzheimer’s disease (10–15 times higher). |
| APOE | e3/e4 or e2/e4 | You have one copy of the APOE e4 allele, which increases your risk of developing Alzheimer’s disease (2–3 times higher). |
| APOE | e3/e3 | You have two copies of the common APOE e3 allele, which has a neutral effect on your risk of Alzheimer’s disease. |
| APOE | e2/e2 or e2/e3 | You have one or two copies of the APOE e2 allele, which may decrease your risk of developing Alzheimer’s disease. |
The APOE e4 allele is a strong genetic risk factor for late-onset Alzheimer’s disease, which accounts for the majority of Alzheimer’s cases. However, having the APOE e4 allele doesn’t mean you will definitely develop the disease. Other factors like age, lifestyle, and environmental conditions also contribute to your overall risk.
Frequently Asked Questions
How long does it take to get results?
Once your sample is received by our laboratory, processing usually takes 6-8 weeks. You will receive an email notification when your results are ready, and you can access your detailed report through a secure online portal.
Is my genetic information kept private?
We take data privacy seriously. Your results are confidential and only shared with you. We do not share your results with insurance companies, employers, or any other third parties.
Why DNA Tests Direct?
Accredited Excellence
Our laboratory holds globally recognized accreditations including AABB, CAP, CLIA, SCC, and ISO17025, ensuring accurate results for every test.
Your Privacy, Protected
Your privacy is our top priority. Our secure, accredited laboratory and password-protected online portal guarantee that your results are shared only with you.
Expert Support
Our dedicated customer care team is here to support you through the process, answer your questions, and provide any assistance you need.